According to the literature, the prevalence of DKD in patients with type 2 DM in China is 10–40% ( 1). Accepted for publication Nov 18, 2021.ĭiabetic kidney disease (DKD) is a common and serious complication of diabetes mellitus (DM). Keywords: Diabetic kidney disease (DKD) syndrome elements traditional Chinese medicine (TCM) diagnostic scale A small-sample clinical validation test of the scale showed sensitivity of 78.8–100%, specificity of 84.3–100%, and accuracy of 82.7–100%.Ĭonclusions: We constructed a TCM syndrome elements diagnostic rating scale for DKD, providing a basis for the standardized study of TCM syndromes. After extracting the syndrome elements, a TCM syndrome elements diagnostic rating scale for DKD containing 9 syndrome elements was constructed, which were qi deficiency syndrome, blood deficiency syndrome, yin deficiency syndrome, yang deficiency syndrome, excessive heat syndrome, qi stagnation syndrome, damp heat syndrome, blood stasis syndrome and phlegm turbidity syndrome. Results: There were 61 items of TCM diagnostic descriptions, and we kept the most useful 32 after filtering. By using the above statistical methods, TCM syndrome elements diagnostic scale was constructed, and confirmed via diagnostic tests of 150 patients. Regression coefficient was used to determine the scale items, and the diagnostic threshold was established by receiver operating characteristic curve. Correlation coefficient and regression analysis were used to determine the syndrome elements. Cluster analysis and factor analysis method were used to identify the syndrome elements.
Frequency dominance method was used to screen the core items. TCM symptoms, signs and tongue manifestation information of the patients were collected, which constituted the items of the TCM syndrome elements diagnostic scale.
Methods: A total of 492 DKD patients were included in the study.
Background: To construct a traditional Chinese medicine (TCM) syndrome elements diagnostic scale for diabetic kidney disease (DKD).